Disease Specialties

Clinical Research Opportunities Include:

Weight Management & Metabolic Diseases

General Information:

Excess body weight represents one of the most prevalent and fast-growing health conditions in the United States. Over
40% of the US population is obese. This is associated with increased risks of medical conditions that include type 2
diabetes, hypertension, dyslipidemia, strokes, sleep apnea, and arthritis. Weight loss of as little as 5-10% can help with the
reduction of these increased risks.

Weight Loss Trials

General Information:

Clinical trials for weight loss are pivotal in evaluating the safety and efficacy of various interventions aimed at addressing the global challenge of obesity. Clinical trials for weight loss contribute valuable insights to the development of evidence-based strategies that can help individuals

Common Qualifications:

High blood pressure
Diabetes
High Cholesterol

Vaccines

General Information:

Vaccines play a critical role in public health by preventing the spread of infectious diseases and protecting individuals and communities from illness. Vaccines and vaccine research trials are essential components of public health strategies, contributing to disease prevention, community immunity, and global health security. They represent a powerful tool in the fight against infectious diseases, saving lives and improving overall well-being.

Flu Vaccine

General Information:

Arizona Clinical Trials is conducting research studies using investigational medications (study drugs) to determine if the study drug is effective against the flu virus. Participants will have between 3 & 5 in person visits and up to 6 virtual appointments over the duration of the study (6-12 months).

Common Qualifications:

Norovirus Vaccine

General Information:

Arizona Clinical Trials is conducting research studies using investigational vaccines to determine if the study drug is effective in prevention of moderate or severe nausea, vomiting and diarrhea associated with norovirus.
Participants will have 7 in person visits and up to 6 virtual appointments over the duration of the study (25 months).

Common Qualifications:

Fatty Liver Disease / MASH / Cirrhosis

General Information:

Fatty liver disease, previously known as NAFLD/NASH, is now called Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Metabolic Dysfunction-Associated Steatohepatitis (MASH). This condition involves fat buildup in the liver, causing inflammation and damage.

Common Qualifications:

Fatty Liver Disease (MASLD): Fat accumulates in the liver due to metabolic issues, potentially leading to liver damage.
MASH: More severe form of fatty liver disease with inflammation and liver cell damage.
Cirrhosis is a condition where the liver becomes heavily scarred (or fibrotic); this can occur as a result of alcohol, viral hepatitis, fatty liver disease, or any other type of chronic liver disease.

Clinical trials for MASLD, MASH, and Cirrhosis play a pivotal role in advancing our understanding and treatment options for these liver conditions.

Fatty Liver Disease

General Information:

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is the buildup of excess fat in the liver, commonly related to diabetes, obesity, genetics, medication, and/or diet. MASLD affects 30-40% of adults in the US, according to the National Institute of Health (NIH), and is rapidly becoming the most common form of liver disease worldwide.

Common Qualifications:

MASH

General Information:

Metabolic Dysfunction-Associated Steatohepatitis (MASH)is defined by the accumulation of fat in the liver, not caused by excessive alcohol use. Known as the silent killer, MASH often has no symptoms until it has progressed. If symptoms do appear, they can include weight loss, fatigue, loss of appetite, abdominal pain, jaundice, swelling in the legs or abdomen as well as confusion.

Common Qualifications:

Cirrhosis

General Information:

Cirrhosis is a condition where the liver becomes heavily scarred (or fibrotic); this can occur as a result of alcohol, viral hepatitis, fatty liver disease, or any other type of chronic liver disease. Many patients with cirrhosis have no associated symptoms. This is why cirrhosis is often diagnosed when the late-stage complications of advanced liver disease develop. Fatigue is common with cirrhosis. When patients begin to develop advanced cirrhosis, they may have evidence of muscle loss, jaundice, edema, or fluid build-up in the abdomen called ascites.

Common Qualifications:

PBC & PSC

General Information:

Clinical trials for liver diseases such as, Primary Biliary Cholangitis (PBC) and Primary Sclerosing Cholangitis (PSC) are instrumental in advancing medical research and developing effective treatments. The outcomes of these trials contribute significantly to the evolving landscape of liver disease management, providing valuable insights into potential breakthroughs and offering hope for improved therapeutic options

Viral Hepatitis

General Information:

Clinical trials focused on viral hepatitis are critical for developing more effective treatments. Viral hepatitis, including hepatitis B and C, poses significant global health challenges, leading to liver inflammation and potentially severe complications such as cirrhosis and liver cancer. Clinical trials in this field aim to evaluate new antiviral medications, therapeutic strategies, and preventive measures to improve the health outcomes of patients worldwide.

Common Qualifications:

Diabetes (Type 1 & 2), Diabetic Neuropathic Pain

General Information:

Type 2 Diabetes is a metabolic condition that can be caused by impaired glycemic control due to increased insulin resistance and failure in inadequate insulin secretion. Type 2 Diabetes is frequently associated with comorbidities such as increased weight or obesity, hypertension, and high cholesterol.

Nephrology

General Information:

About 30% of patients with Type 1 diabetes and 10-40% with Type 2 diabetes eventually will suffer from kidney failure according to the National Kidney Foundation. Studies for patients with CKD are critical to improve the lives of patients and maintaining and restoring kidney health.

Common Qualifications:

Neurology (Phase 1 Only)

General Information:

Neurology studies are essential for advancing our understanding of the brain and nervous system. They help researchers develop better treatments for conditions like Alzheimer’s, Parkinson’s, epilepsy, multiple sclerosis, and stroke. By participating in these studies, individuals contribute to discoveries that can improve quality of life and lead to earlier diagnoses, more effective therapies, and, ultimately, hope for millions affected by neurological disorders.

Neurology

General Information:

Neurology studies also provide critical insight into how the nervous system responds to new medications, helping ensure treatments are both safe and tailored to support brain and nerve health.

Common Qualifications:

Dermatology

General Information:

Dermatology studies focus on understanding and improving the health of the skin, hair, and nails. They play a key role in developing new treatments for conditions like eczema, psoriasis, acne, skin infections, and even skin cancer. These studies help researchers test how well new therapies work and ensure they are safe and effective for different skin types and needs.

Dermatology

General Information:

By participating in dermatology studies, individuals can contribute to breakthroughs that lead to more personalized and accessible skincare solutions for people of all ages.

Enrolling Trials